MyBioSource.com's CD18 antibody (biotin) is a Rat monoclonal antibody. The CD18 antibody (biotin) was generated using Miscellaneous as the antigen. It reacts with Zebrafish/Fish. This antibody has been shown to work in applications such as: Flow Cytometry, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Rat monoclonal CD18 antibody (biotin)
Integrin beta-2 (CD18) is a protein that in humans is encoded by the ITGB2 gene. The ITGB2 protein product is the integrin beta chain beta 2. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. In humans lack of CD18 causes Leukocyte Adhesion Deficiency, a disease defined by a lack of leukocyte extravasation from blood into tissues